We Build Profitable Urine Drug Testing Laboratories

Medical Source integrates the most advanced screening, confirmation, and workflow technologies into a single turn-key solution — so your lab delivers the highest data quality at the lowest cost per reportable result. Since 1992. All 50 states.

Schedule a Free Consultation → See How It Works ↓
30+ Years of Expertise
50 States Served
20+ Year Client Relationships
100% Turn-Key Service

The Integrated Workflow

⚗

Immunoassay Screening

CEDIA & DRI on clinical chemistry analyzers. 40+ drug classes. Results in under 30 minutes.

◈

Chromatography-Free LC-MS/MS

DART triple quad MS. 96 samples in 42 min. 15× faster than traditional LC-MS.

▣

Pre-Validated Consumable Kits

NIST-traceable panels pre-plated on 96-well plates. 30–40% faster processing.

The Medical Source Toxicology Workflow

Three Integrated Capabilities. One Seamless Lab.

We assemble the most effective technologies at each stage of the drug testing process — and wrap them in 30+ years of consulting expertise to make it all work together from day one.

1
Stage 1 · Presumptive Screening

Gold-Standard Immunoassay Detection

Rapid, accurate identification of drug classes using the world's leading immunoassay technologies — proven across thousands of labs globally for nearly four decades.

CEDIA technology — genetically engineered enzyme fragments with superior specificity
DRI technology — homogeneous enzyme immunoassay with liquid ready-to-use reagents
40+ drug classes — opioids, benzodiazepines, amphetamines, cannabinoids, fentanyl, buprenorphine, EtG, and more
Specimen validity testing — pH, specific gravity, oxidants, creatinine
Under 30 minutes — results with no sample pretreatment steps
Platform agnostic — compatible with all major clinical chemistry analyzers
2
Stage 2 · Definitive Confirmation

Chromatography-Free Mass Spectrometry

Next-generation triple quadrupole MS with integrated DART (Direct Analysis in Real Time) ionization — purpose-built for routine toxicology labs that need definitive results without the complexity of traditional LC-MS.

96 samples in 42 minutes — up to 15× faster than traditional LC-MS workflows
DART + LC-MS dual source — seamless switch to conventional LC-MS in seconds when needed
1,000 MRMs/second — comprehensive large-panel screening and confirmation
95% solvent reduction — dramatically lower operating costs vs. traditional LC-MS
Benchtop footprint — operable by existing medical technologists, no chromatography expertise
Results in ng/ml — the only methodology Medicare and private payers reimburse for confirmation
3
Stage 3 · Workflow Optimization

Pre-Validated Ready-to-Use Consumables

The consumable backbone connecting your screening and confirmation into one efficient operation. Eliminates tedious, error-prone manual standard preparation.

Pre-plated 96-well plates — calibrators, QCs, and NIST-traceable internal standards ready to go
ANSI/ASB Standard 036 — pre-validated panels for opioids, benzodiazepines, cannabinoids, barbiturates, stimulants, antidepressants
Suspended-state technology — all-in-one plates with enzyme buffer and β-glucuronidase in frozen solid state
30–40% faster processing — fewer manual movements, fewer errors
Custom panel builds — your molecules, concentrations, and plate layout
PhD toxicologist consulting — method validation, analyst training, workflow optimization
Why This Combination Changes Everything

The Most Cost-Effective Toxicology Operation Available Today

Each technology is exceptional on its own. Together — with three decades of integration expertise — they create unmatched clinical and financial performance.

⚡

Fastest Turnaround in the Market

Screening in under 30 minutes. Confirmation of 96 samples in 42 minutes. Pre-validated consumables cut prep time by a third. Faster results mean better clinical decisions for patients and ordering physicians.

15× faster confirmation than traditional LC-MS
◆

Lowest Cost Per Reportable Result

Chromatography-free confirmation slashes solvent costs by 95%. Ready-to-use consumables eliminate manual standard preparation. Fewer re-runs from higher accuracy. We model the math for your specific volume before you commit.

95% less solvent waste = dramatically lower operating costs
◎

Detect What Others Miss

New synthetic drugs appear constantly — carfentanyl, kratom, K2, bath salts, designer opioids. Our screening menu covers 40+ drug classes, and our confirmation identifies 133+ specific compounds with definitive quantitative precision.

40+ drug classes · 133+ specific compounds identified
◈

Built for Maximum Reimbursement

Medicare and private payers require LC-MS methodology for confirmation — that is exactly what we deploy. Our billing partners ensure optimal credentialing while we navigate PAMA and MACRA changes to protect your revenue.

LC-MS confirmation = payer-compliant from day one
◇

Your Existing Staff Can Run It

Traditional LC-MS requires experienced chromatographers who are expensive and hard to find. Our chromatography-free confirmation system is designed for routine lab environments — your existing medical technologists operate it with our training.

No chromatography expertise required
◉

We Stay and Optimize for Years

Most consultants disappear after launch. Medical Source offers ongoing advisory partnerships — overseeing operations, watching reimbursement changes, optimizing your test menu, and ensuring profitability and compliance year after year.

20+ year client relationships and counting
Lab Setup & Startup

From First Conversation to First Patient Result

Our proven five-stage process takes you from initial feasibility assessment through a fully operational, CLIA-compliant urine toxicology laboratory.

1

Discovery & Feasibility

Goals, patient base, volume projections, budget. Honest financial feasibility assessment.

2

Regulatory & Design

CLIA, COLA, state applications. Physical lab layout. Customized test menu.

3

Instrument Selection

Screening platform, mass spectrometer, consumable workflow — sized for your volume.

4

Validation & Go-Live

Method validation, staff training, LIS/EMR integration, billing, inspection prep, launch.

5

Ongoing Advisory

Operations optimization, reimbursement tracking, test menu updates, profitability protection.

Additional Services

Beyond Toxicology — Full Clinical Laboratory Support

Urine toxicology is our flagship. Medical Source also supports every aspect of clinical laboratory operations.

🧬

Molecular Testing — PGx & CGx

Pharmacogenomic testing for drug metabolism (cardiology, oncology, pain management, psychiatry profiles). Cancer genomics for inherited mutations. Respiratory pathogen panels.

📊

Profitability & Reimbursement Consulting

Navigate PAMA reimbursement reductions and MACRA transitions. Optimize test menus, workflows, and billing strategies to protect and grow your bottom line.

🛡

CLIA/COLA Compliance & QA

Accreditation support, deficiency correction, plan-of-correction drafting, QC/QA programs, standard operating procedures, and complete inspection preparation.

🔬

Instrumentation Selection

Unbiased recommendations across nearly every major manufacturer — chemistry, hematology, immunoassay, molecular. Sized precisely to your data and volume requirements.

💻

LIS, Middleware & EMR Integration

Laboratory information systems, middleware solutions, EMR/web-portal interfaces, billing modules, and customized reporting for seamless clinical workflows.

👥

Staff Recruitment & Training

Screening, recruiting, and onboarding medical technologists, analytical chemists, and molecular scientists for your laboratory operation.

Who We Serve

Built for Every Practice Type

Medical Source builds and supports urine drug testing laboratories for practices of all sizes and specialties across all 50 states.

Pain Management Behavioral Health & Addiction Treatment Family Medicine Urgent Care Reference Laboratories Internal Medicine Nephrology Oncology Rheumatology Cannabis Testing Labs Physician-Owned Labs Group Practices
Frequently Asked Questions

What Lab Owners Ask Us Most

A urine drug testing lab performs two tiers of analysis. Tier 1 — Presumptive Screening uses immunoassay technology (CEDIA and DRI) on clinical chemistry analyzers to detect drug classes, with results in under 30 minutes. Tier 2 — Definitive Confirmation uses triple quadrupole mass spectrometry (LC-MS/MS) to identify specific substances and metabolites, reported in ng/ml. Medicare and private payers require LC-MS methodology for confirmation reimbursement. Medical Source provides the complete integrated workflow for both tiers.

Costs vary based on testing volume, instrument selection, facility requirements, and staffing. Medical Source provides free feasibility consultations to assess your specific situation — including volume projections, test menu requirements, and financial modeling. We also help secure financing. Call 770-642-9155 for a no-obligation conversation.

Chromatography-free MS uses DART (Direct Analysis in Real Time) ionization to eliminate the liquid chromatography step that creates bottlenecks in traditional drug testing. This processes 96 samples in about 42 minutes — up to 15× faster — with lower cost per test, 95% less solvent waste, and operation by staff without chromatography expertise. Medical Source deploys this as the confirmation backbone for the toxicology labs we build.

We deploy two gold-standard technologies: CEDIA (Cloned Enzyme Donor Immunoassay), which uses genetically engineered beta-galactosidase fragments for superior specificity, and DRI (Drug Reagent Immunoassay), which uses G6PDH in a homogeneous format with liquid ready-to-use reagents. Both run on major clinical chemistry analyzers, require no pretreatment, and cover 40+ drug classes including opioids, benzodiazepines, amphetamines, cannabinoids, fentanyl, buprenorphine, synthetic cannabinoids, and EtG.

Pre-validated panels are ready-to-use kits with calibrators, quality controls, and NIST-traceable internal standards pre-plated on 96-well plates. Remove from freezer, add samples, analyze — eliminating hundreds of manual preparation steps. Panels validated to ANSI/ASB Standard 036 cover opioids, barbiturates, benzodiazepines, cannabinoids, stimulants, antidepressants, and more. Labs report 30–40% faster processing with improved accuracy and precision.

You need CLIA certification, typically COLA or equivalent accreditation, and applicable state licenses. Medical Source handles the entire regulatory process — applications, QC/QA programs, standard operating procedures, proficiency testing, method validation, and inspection preparation for all 50 states.

Yes — we serve all 50 states. Based in Marietta, Georgia (near Atlanta), Medical Source has provided clinical laboratory consulting nationwide since 1992. Our clients include reference labs, individual practitioners, group practices, urgent care, behavioral health, pain management, oncology, nephrology, and more.

Unbiased guidance — we work with nearly every manufacturer, so recommendations fit your needs, not a brand. Truly turn-key — from regulatory applications through installation, validation, hiring, billing, and inspection preparation. Ongoing partnership — we stay on to optimize operations and profitability for years, not just through launch. Many relationships have lasted 20+ years.

Our screening and confirmation workflow detects over 40 drug classes and identifies 133+ specific compounds, including opioids, benzodiazepines, amphetamines, cannabinoids, fentanyl, buprenorphine, synthetic cannabinoids (K2, Spice), bath salts, carfentanyl, kratom, designer opioids, EtG (ethyl glucuronide for alcohol), barbiturates, stimulants, antidepressants, and many more. Custom panels can be built for specific patient populations and clinical needs.

Pain management clinics, behavioral health and addiction treatment centers, family medicine practices, urgent care facilities, reference laboratories, internal medicine, nephrology, oncology, rheumatology, and cannabis testing labs all benefit from in-house urine toxicology testing. In-house testing offers faster turnaround, better patient care, greater control over quality, and the ability to recapture revenue currently sent to external reference labs.

Ready to Build the Most Efficient Toxicology Lab in Your Market?

One conversation is all it takes. We will walk you through how our integrated screening, confirmation, and consumable workflow comes together — and model what it looks like for your specific operation. No pressure. Just 30+ years of straight answers.

📞 770-642-9155